Publication: Evolutionary and sequence-based relationships in bacterial AdoMet-dependent non-coding RNA methyltransferases
col.comunidadvinculada | Comunidad científica colombiana | es_CO |
col.contrato | 0020-2013 | es_CO |
col.date.proyecto | 2015-08-10 | |
col.programa.colciencias | Programa Nacional de Biotecnología | es_CO |
col.tipo.esp | Artículos de investigación | es_CO |
dc.audience | Entidades gubernamentales | es_CO |
dc.audience | Profesores | es_CO |
dc.audience | Investigadores | es_CO |
dc.coverage.spatial | Colombia | es_CO |
dc.creator | Benítez Páez, Alfonso | |
dc.creator | Mosquera Rendón, Jeanneth | |
dc.creator | Cárdenas Brito, Sonia | |
dc.creator | Pineda, Juan D. | |
dc.creator | Corredor Rodríguez, Mauricio | |
dc.creator.corporativo | Centro de Investigación y Desarrollo en Biotecnología | es_CO |
dc.creator.corporativo | Universidad de Antioquia, UdeA | es_CO |
dc.creator.corporativo | Universidad Cooperativa de Colombia, UCC | es_CO |
dc.date.accessioned | 2019-03-25T18:18:18Z | |
dc.date.available | 2019-03-25T18:18:18Z | |
dc.date.issued | 2014 | |
dc.description.abstract | RNA post-transcriptional modification is an exciting field of research that has evidenced this editing process as a sophisticated epigenetic mechanism to fine tune the ribosome function and to control gene expression. Although tRNA modifications seem to be more relevant for the ribosome function and cell physiology as a whole, some rRNA modifications have also been seen to play pivotal roles, essentially those located in central ribosome region. RNA methylation at nucleobases and ribose moieties of nucleotides appear to frequently modulate its chemistry and structure. RNA methyltransferases comprise a superfamily of highly specialized enzymes that accomplish a wide variety of modifications. These enzymes exhibit a poor degree of sequence similarity in spite of using a common reaction cofactor and modifying the same substrate type. | es_CO |
dc.description.isproject | no | es_CO |
dc.description.projectid | 5817-569-34856 | es_CO |
dc.description.projectname | Establecimiento de módulo funcionales de secuencia en familias de metiltransferasas de RNA y su uso en la búsqueda de genes de resistencia a antibióticos en patógenos humanos | es_CO |
dc.description.sponsorship | Departamento Administrativo de Ciencia, Tecnología e Innovación [CO] Colciencias | es_CO |
dc.format | es_CO | |
dc.format.extent | 15 páginas | es_CO |
dc.identifier.bibliographicCitation | Contiene 106 referencias bibliográficas. Véase el documento adjunto | es_CO |
dc.identifier.issn | 1756-0500 | |
dc.identifier.uri | http://repositorio.colciencias.gov.co/handle/11146/34128 | |
dc.language.iso | eng | es_CO |
dc.relation.ispartof | Establecimiento de módulos funcionales de secuencia en familias de metiltransferasas de RNA y su uso en la búsqueda de genes de resistencia a antibióticos en patógenos humanos. La publicación completa está disponible en : <a href="http://repositorio.colciencias.gov.co/handle/11146/34125" target="blank">http://repositorio.colciencias.gov.co/handle/11146/34125</a> | es_CO |
dc.rights | info:eu-repo/semantics/openAccess | es_CO |
dc.source | BMC Research Notes 2014, 7:440. 1-15 | es_CO |
dc.subject.keyword | Molecular evolution | es_CO |
dc.subject.keyword | Conserved sequnce motifs | es_CO |
dc.subject.keyword | Antibiotic resistance | es_CO |
dc.subject.keyword | RNA methyltransferases | es_CO |
dc.subject.spines | Bioquímica | es_CO |
dc.subject.spines | Bacterias | es_CO |
dc.subject.spines | Secuencia de aminoácidos | es_CO |
dc.subject.spines | Penisilinas | es_CO |
dc.title | Evolutionary and sequence-based relationships in bacterial AdoMet-dependent non-coding RNA methyltransferases | es_CO |
dc.type | Artículo científico | es_CO |
dc.type.driver | info:eu-repo/semantics/article | es_CO |
dc.type.hasversion | info:eu-repo/semantics/publishedVersion | es_CO |
dspace.entity.type | Publication |