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In vitro validation of Quantitative Light-induced Fluorescence (QLF) for the diagnosis of enamel fluorosis in permanent teeth

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col.comunidadvinculadaComunidad odontológica colombianaes_CO
col.contrato0442-2012es_CO
col.date.proyecto2016-12
col.programa.colcienciasPrograma de Ciencia y Tecnología e Innovación en Saludes_CO
col.tipo.espGeneración de contenidos impresos, radiales, audiovisuales, multimedia, virtuales y Creative Commonses_CO
dc.audienceProfesoreses_CO
dc.audienceInvestigadoreses_CO
dc.coverage.spatialColombiaes_CO
dc.creatorCuevas Espinosa, Diana Milena
dc.creatorMartínez Mier, Esperanza Ángeles
dc.creatorMasatoshi, Ando
dc.creatorCastiblanco Rubio, Gina Alejandra
dc.creatorCortés, Fabián
dc.creatorRincón Bermúdez, Claudia Milena
dc.creatorMartignon Biermann, Stefania
dc.creator.corporativoUniversidad El Bosque - UNICA, Caries Research Unites_CO
dc.creator.corporativoIndiana University School of Dentistry, IUSDes_CO
dc.creator.mailmartignonstefania@unbosque.edu.coes_CO
dc.date.accessioned2019-03-26T20:40:18Z
dc.date.available2019-03-26T20:40:18Z
dc.date.embargoEndinfo:eu-repo/date/embargoEnd/2024-01-31es_CO
dc.date.issued2015
dc.description.abstractThe use of Quantitative Light-induced Fluorescence (QLF) for the diagnosis of enamel fluorosis has not been validated. This study aimed to validate QLF as a diagnostic tool for mild and moderate fluorosis in permanent teeth, comparing it to visual diagnosis and histological assessment completed using polarized light microscopy (PLM). The buccal surfaces of 139 teeth were visually classified using the Thylstrup and Fejerskov Index (TFI) into sound (TFI 0; n=17), mild (TFI 1-2; n=69) and moderate (TFI 3-4; n=43) fluorosis. Fluorosis was then assessed with QLF using the entire surface and a region of interest (ROI), identified as the most representative region of a fluorosis lesion. PLM images of longitudinal thin sections including the ROI were assessed for histological changes. Correlations among TFI, PLM, and QLF were determined. A ROC curve was conducted to determine QLF’s diagnostic accuracy when compared to the TFI and PLM assessments. This was used to assess the probability that the images were correctly ranked according to severity as determined by PLM and TFI. A positive correlation was found between QLF and PLM, and between QLF and TFI. QLF showed highest sensitivity and specificity for the diagnosis of mild fluorosis. There was also a strong agreement between TFI and PLM. The selection of a ROI resulted in a stronger correlation with TFI and PLM than when the entire surface was used. The study results indicate that defining a ROI for QLF assessments is a valid method for the diagnosis of mild and moderate enamel fluorosis.es_CO
dc.description.isprojectnoes_CO
dc.description.projectid1308-569-34427es_CO
dc.description.projectnameModelo de caracterización ambiental, epidemológica, clínico-histológica e inorgánica de la fluorosis dental en niñoses_CO
dc.description.sponsorshipDepartamento Administrativo de Ciencia, Tecnología e Innovación [CO] Colcienciases_CO
dc.formatpdfes_CO
dc.format.extent22 páginases_CO
dc.identifier.bibliographicCitationContiene 45 referencias bibliográficas. Véase el documento adjuntoes_CO
dc.identifier.urihttp://repositorio.colciencias.gov.co/handle/11146/34150
dc.language.isoenges_CO
dc.relation.ispartofModelo de caracterización ambiental, epidemiológica, clínico-histológica e inorgánica de la fluorosis dental en niños. La publicación completa está disponible en : <a href="http://repositorio.colciencias.gov.co:80/handle/11146/34140" target="blank">http://repositorio.colciencias.gov.co:80/handle/11146/34140</a>es_CO
dc.rightsinfo:eu-repo/semantics/embargoedAccesses_CO
dc.subject.lembEnamel fluorosises_CO
dc.subject.lembFluoridees_CO
dc.subject.lembQuantitative light fluorescencees_CO
dc.subject.lembPermanent teethes_CO
dc.subject.spinesFlour -- Investigacioneses_CO
dc.subject.spinesFluorosis dentales_CO
dc.subject.spinesCaries dentales_CO
dc.subject.spinesCaries -- Estudios de casoses_CO
dc.titleIn vitro validation of Quantitative Light-induced Fluorescence (QLF) for the diagnosis of enamel fluorosis in permanent teethes_CO
dc.typeOtroses_CO
dc.type.driverinfo:eu-repo/semantics/other.generacióndecontenidoses_CO
dc.type.hasversioninfo:eu-repo/semantics/draftes_CO
dspace.entity.typePublication

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