Publication:
Chemical Composition of Salvia aratocensis Extract obtained by Supercritical Fluid Extraction and its Antigenotoxicity against Ultraviolet Radiation-Induced DNA Damage

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col.comunidadvinculadaComunidad científica colombianaes_CO
col.contrato0572-2012es_CO
col.date.proyecto2018-01
col.programa.colcienciasProgramas de CT+I Ejecutados por Redes de Conocimientoes_CO
col.tipo.espArtículos de investigaciónes_CO
dc.audienceAdministradores de ciencia y tecnologíaes_CO
dc.audienceInvestigadoreses_CO
dc.coverage.spatialColombiaes_CO
dc.creatorFuentes Lorenzo, Jorge Luis
dc.creatorStashenko, Elena E.
dc.creatorQuintero Ruiz, Nathalia
dc.creator.corporativoBio-Red-CO-CENIVAMes_CO
dc.creator.corporativoUniversidad Industrial de Santander, UISes_CO
dc.creator.mailelena@tucan.uis.edu.coes_CO
dc.date.accessioned2019-03-31T22:49:52Z
dc.date.available2019-03-31T22:49:52Z
dc.date.embargoEndinfo:eu-repo/date/embargoEnd/2024-01-31es_CO
dc.date.issued2015
dc.description.abstractSalvia is a cosmopolitan and important genus, widely used in flavoring and traditional medicine for treatments of respiratory and gastrointestinal diseases. The present work evaluated the chemical composition of Salvia aratocensis extract obtained by supercritical CO2 extraction, as well as its DNA protective effect against ultraviolet radiation (UVR)-induced genotoxicity. S. aratocensis extract composition was determined by gas chromatography-mass spectrometry (GCMS). The antigenotoxic effect of S. aratocensis extract was assayed in co-incubation procedures using the SOS chromotest in Escherichia coli PQ37 cells. The major components of the plant extract were α-cadinol (31.8%), 1,10-epi-cubenol (12.9%), trans-β-caryophyllene (7.7%), -cadinene (6.6%), and squalene (6.5%). S. aratocensis extract protected bacterial cells against UVR-induced genotoxicity at doses between 0.063 and 1 mg/mL. The results were discussed in relation to the DNA protective potential of the S. aratocensis extract and its major constituents.es_CO
dc.description.isprojectnoes_CO
dc.description.projectid5507-543-31904es_CO
dc.description.projectnamePrograma: Bioprospección y desarrollo de ingredientes naturales para las industrias cosmética, farmacéutica y de productos de aseo con base en la biodiversidad colombianaes_CO
dc.description.sponsorshipDepartamento Administrativo de Ciencia, Tecnología e Innovación [CO] Colcienciases_CO
dc.formatpdfes_CO
dc.format.extent5 páginases_CO
dc.identifier.bibliographicCitationContiene 34 referencias bibliográficas. Véase documento adjuntoes_CO
dc.identifier.issn1934-578X
dc.identifier.issn1555-9475
dc.identifier.urihttp://repositorio.colciencias.gov.co/handle/11146/34154
dc.language.isoenges_CO
dc.relation.ispartofPrograma: Bioprospección y desarrollo de ingredientes naturales para las industrias cosmética, farmacéutica y de productos de aseo con base en la biodiversidad colombiana. La publicación completa está disponible en : <a href="http://repositorio.colciencias.gov.co/handle/11146/34163" target="blank">http://repositorio.colciencias.gov.co/handle/11146/34163</a>es_CO
dc.rightsinfo:eu-repo/semantics/embargoedAccesses_CO
dc.sourceNatural Product Communications Vol. 10 (0) 2015 pp. 1-5es_CO
dc.subject.keywordSalvia aratocensis
dc.subject.keywordSupercritical CO2 extraction
dc.subject.keywordAntigenotoxicity
dc.subject.keywordSOS Chromotest
dc.subject.keywordUltraviolet radiation
dc.subject.spinesAceites esencialeses_CO
dc.subject.spinesQuímica agrícolaes_CO
dc.subject.spinesAceites esencialeses_CO
dc.subject.spinesAceites combustibleses_CO
dc.subject.spinesBioquímica vegetales_CO
dc.subject.spinesBotánicaes_CO
dc.subject.spinesBiotecnologíaes_CO
dc.titleChemical Composition of Salvia aratocensis Extract obtained by Supercritical Fluid Extraction and its Antigenotoxicity against Ultraviolet Radiation-Induced DNA Damagees_CO
dc.typeArtículo científicoes_CO
dc.type.driverinfo:eu-repo/semantics/articlees_CO
dc.type.hasversioninfo:eu-repo/semantics/publishedVersiones_CO
dspace.entity.typePublication

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