Gore Saravia, Nancy2023-12-222023-12-222001-08-31https://repositorio.minciencias.gov.co/handle/20.500.14143/501001 documentoDuring their life cycle, Leishmania parasites multiply as flagellated promastigotes within the alimentary tract of the sand fly vector (genus Lufzomyia) and subsequently migrate anteriorly. During feeding, the sand fly transmits flagellated promastigotes to the mammalian host that enter macrophages and transform into aflagellated amastigotes. The presence of a flagellum consisting of an axonema and a lattice-like structure known as the Paraflagellar Rod (PFR), which has a role in the flagellar moti lit y of the parasite, is a distinguishing characteristic of the promastigote stage.22 p.application/pdfspaInforme de investigaciónVacunasProyectos de investigacióninfo:eu-repo/semantics/openAccessAtribución 4.0 Internacional (CC BY 4.0)ParásitosLeishmaniaInmunización