2019-04-012019-04-0120131875-5348http://repositorio.colciencias.gov.co/handle/11146/34189Diverse natural product-like N-benzyl cinnamamides were prepared by condensation of trans-cinnamic acid with substituted benzylamines in the presence of boric acid as catalyst. The further evaluation of this amides as a substrates of the bromo-arylation reaction, in the presence of N-bromosuccinimide (NBS) as the halogen source and under the catalysis of Yb(OTf)3, generate a different types of N-substituted amides: N-aryl 2,3-dibromopropanamides, N-(2-bromobenzyl) cinnamamides and tetrahydro-2-benzazepin-3-one as a new molecules. Here we discuss the formation of these main products on the basis of the electronic nature of the substituents present in the N-benzyl aromatic ring of the prepared cinnamamides.pdf10 páginasenginfo:eu-repo/semantics/embargoedAccessArtículo científicoContiene 27 referencias bibliográficas. Véase documento adjuntoBiología vegetalProductos farmacéuticosPlantas medicinalesN-Aryl 2,3-dibromopropanamidesN-Benzyl cinnamamidesBoric acidN-(2-Bromobenzyl) cinnamamidesTetrahydro-2- benzazepin-3-onesYb(OTf)3-Catalyzed bromination reactionsTecnología químicaBioquímica vegetalBiomasaAceites esenciales